Bishop Broderick Pabillo led the procession, which started at 5 am. Veritas Asia president Father Anton Pascual joined in the 6th station near the Bayview Hotel.
Manila Archbishop Luis Antonio Cardinal Tagle later led the devotees to Manila Cathedral.
Tagle told the devotees that Filipinos should be proactive in the fight against the spread of a "death culture". (WATCH: Cardinal Tagle leads Good Friday 'Walk for Life')